TENTATIVE PROGRAM
| DAY 1: 24 AUGUST 2009, MONDAY, 8.00AM – 6.00PM | ||
| REGISTRATION | ||
| 08:00-08:45 | Registration | |
| 09:00-09:15 |
Welcome & Introductions Huck Hui NG |
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| SESSION 1: Epigenomics Chair: Huck Hui NG (GIS, Singapore) |
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| 09:15-09:50 |
Ed LIU (GIS, Singapore) Functional Genomics of Estrogen Receptor Binding |
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| 09:50-10:15 |
Alex MEISSNER (Broad Institute, USA) Epigenomics, Stem Cells and Reprogramming |
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| 10:15-10:40 |
Bing REN (UCSD, USA) Chromatin signatures of transcriptional enhancers and beyond |
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| 10:40-11:10 | MORNING COFFEE and POSTER SESSION | |
| SESSION 2: Epigenomics I Chair: Edwin CHEUNG (GIS, Singapore) |
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| 11:10-11:35 |
Hiroyuki ABURATANI (University of Tokyo, Japan) Epigenomic profiling of cancer |
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| 11:35-12:00 |
Guoliang XU (Shanghai Institute of Biochemistry and Cell Biology, China) The Chromatin Determinant of Genomic Methylation |
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| 12:00-12:25 |
Marian WALHOUT (UMass Medical School, USA) Gene-centered regulatory networks |
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| 12:25-14:00 | LUNCH and POSTER SESSION | |
| 13:00-13:30 | TOUR OF THE GENOME INSTITUTE OF SINGAPORE | |
| SESSION 3: Higher Order Genome Organization Chair: Xinyuan FU (National University of Singapore, Singapore) |
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| 14:00-14:25 |
Edwin CHEUNG (GIS, Singapore) Estrogen Receptor-Mediated Long-Range Chromatin Interactions in Breast Cancer Cells |
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| 14:25-14:50 |
Job DEKKER (UMass Medical School, USA) Three-dimensional folding of chromosomal domains in relation to gene expression |
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| 14:50-15:15 |
Bas VAN STEENSEL (Netherlands Cancer Institute, Netherlands) Nuclear Lamina -- Genome Interactions And Gene Regulation |
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| 15:15-15:40 |
Chia-Lin WEI (GIS, Singapore) Functional Chromatin Organizations Defined by Insulator, Enhancer and Nuclear Lamin in Stem Cell Genomes |
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| 15:40-16:10 | AFTERNOON TEA and POSTER SESSION | |
| SESSION 4: Epigenetics in drug discovery (Lilly-sponsored session) Chair: Jonathon SEDGWICK (Lilly Singapore Centre for Drug Discovery, Singapore) |
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| 16:10-16:35 |
Jonathon SEDGWICK (Lilly Singapore Centre for Drug Discovery, Singapore) Epigenetics - The challenges of drug discovery against unprecedented targets |
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| 16:35-17:00 |
Qiang YU (GIS, Singapore) Combinatorial epigenetic drug treatment targeting histone methylation in cancer |
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| 17:00-17:25 |
Peter JONES (University of Southern California, USA) Epigenetic Therapy |
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| 17:25-17:50 |
Ricky JOHNSTONE (Peter MacCallum Cancer Centre, Australia) Histone deacetylase inhibitors for the treatment of cancer |
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| Back to Top | ||
| DAY 2: 25 AUGUST 2009, TUESDAY, 9.00AM – 5.30PM | ||
| SESSION 5: Stem Cells Chair: Bing LIM (GIS, Singapore) |
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| 09:00-09:25 |
Antoine PETERS (FMI, Switzerland) Epigenetic control of early mouse development: integrating parental contributions into the embryonic program |
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| 09:25-09:50 |
Rho Hyun SEONG (Seoul National University, Korea) The SWI/SNF-like chromatin remodeling complex is an essential transcriptional regulator in the early B cell development |
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| 09:50-10:15 |
Jae-Bum KIM (Seoul National University, Korea) Role of Chromatin Remodeling During Osteoblast Differentiation |
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| 10:15-10:40 |
Paul ROBSON (GIS, Singapore) Insights into Blastocyst Formation Revealed by Single Cell Analysis |
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| 10:40-11:10 | MORNING COFFEE and POSTER SESSION | |
| SESSION 6: Technology Platform Chair: Chunming DING (Singapore Institute for Clinical Sciences, Singapore) |
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| 11:10-11:35 |
Supriya SHIVAKUMAR (Sigma-Aldrich Corporation, USA) Targeted Genome Editing in Mammalian Cells Using Engineered Zinc Finger Nucleases |
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| 11:35-12:00 |
Darryl IRWIN (Sequenom Asia Pacific) Epigenetic target identification |
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| 12:00-13:30 | LUNCH and POSTER SESSION | |
| SESSION 7: Epigenetics in Cancer Chair: Chunming DING (Singapore Institute for Clinical Sciences, Singapore) |
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| 13:30-13:55 |
Yutaka KONDO (Aichi Cancer Center, Japan) Role of histone H3 lysine 27 tri-methylation in human brain tumor-propagating cells |
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| 13:55-14:20 |
Kazu USHIJIMA (National Cancer Centre Research Institute, Japan) The presence of strong target gene specificity in induction of DNA methylation, and its mechanisms |
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| 14:20-14:45 |
Jingde ZHU (Shanghai cancer Institute, China) Cancer Epigenetics(-omics): from DNA methylation perspective |
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| 14:45-15:10 |
Erwei SONG (Sun Yat Sen University, China) MicroRNAs regulate the stemness of breast tumor initiating cells |
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| 15:10-15:40 | AFTERNOON TEA and POSTER SESSION | |
| SESSION 8: Epigenetics 2 Chair: Anne Ferguson SMITH (Singapore Institute for Clinical Sciences, Singapore) |
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| 15:40-16:05 |
Young-Joon KIM (Yosei Unversity, Korea) Intrinsic variability of gene expression encoded in nucleosome positioning sequences |
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| 16:05-16:30 |
Joseph NADEAU (Case Western Reserve University, USA) Transgenerational genetic effects on development and cancer |
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| 16:30-16:55 |
Sam EL-OSTA (Baker IDI Institute, Australia) The clinical problem of hyperglycemic memory and the relevance of the histone tail |
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| 16:55-17:20 |
Ernesto GUCCIONE (IMCB, Singapore) Identification of Novel Epigenetic Regulators |
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| 17.20-17.30 | Closing remarks | |
| 17:45 | Depart for Gala Dinner | |
| 18:30 | Gala Dinner | |